
What you will learn:
This course covers the neurological and immune mechanisms driving CRPS, giving you the scientific foundation to explain the condition clearly to patients and colleagues. You will learn to apply the Budapest Criteria, conduct structured physical examinations, and use validated outcome scales. Pharmacological strategies, including neuropathic agents, anti-inflammatory medications, and opioid risk mitigation, are covered in depth. You will also develop skills in graded rehabilitation, psychological interventions such as CBT and ACT, and interventional procedures including spinal cord stimulation. Special populations, refractory cases, paediatric considerations, and medicolegal documentation are addressed throughout.
How you study in practice CRPS Management Course
How you practise CRPS Management Course
For companies looking to train their teams
With Dedika for businesses, the course includes exercises and examples tailored to your company and its specific needs.
Course content
8 Chapters • 40 LessonsDuration between 4 and 360 hours (you decide)
Chapter 1HideHide detailsSee detailsFoundations of CRPS Pathophysiology
Foundations of CRPS Pathophysiology
Lesson 1 • Psychological and Genetic Predispositions
Identifies biopsychosocial risk factors and genetic markers associated with CRPS vulnerability. Prepares clinicians to screen high-risk patients proactively.
Lesson 2 • Autonomic and Immune System Involvement
Details sympathetic dysregulation, autoimmune hypotheses, and cytokine profiles in CRPS. Connects immune and autonomic dysfunction to observable vasomotor symptoms.
Lesson 3 • Defining CRPS and Its Subtypes
Distinguishes CRPS Type I from Type II and clarifies diagnostic boundaries. Provides the conceptual baseline required for all subsequent clinical reasoning.
Lesson 4 • Central Sensitization and Neuroplasticity
Covers spinal and supraspinal amplification of pain signals and cortical reorganization. Explains why CRPS pain persists beyond initial injury resolution.
Lesson 5 • Peripheral Sensitization Mechanisms
Examines nociceptor sensitization, inflammatory mediators, and tissue-level changes. Links peripheral events to the clinical signs observed at presentation.
Chapter 2HideHide detailsSee detailsClinical Diagnosis and Assessment
Clinical Diagnosis and Assessment
Lesson 1 • Diagnostic Imaging and Laboratory Testing
Reviews the role and limitations of bone scintigraphy, MRI, thermography, and blood panels. Guides appropriate test ordering to support rather than replace clinical diagnosis.
Lesson 2 • Differential Diagnosis Strategies
Distinguishes CRPS from mimicking conditions including neuropathies, vascular disorders, and inflammatory arthritis. Reduces misdiagnosis rates through systematic exclusion.
Lesson 3 • Structured Physical Examination
Teaches a reproducible head-to-toe exam sequence targeting CRPS-specific findings. Ensures consistent data collection across clinical encounters.
Lesson 4 • Validated Pain and Function Scales
Introduces standardised instruments for quantifying pain intensity, disability, and quality of life. Enables outcome tracking and treatment benchmarking.
Lesson 5 • Budapest Criteria in Clinical Practice
Applies the Budapest diagnostic criteria systematically to patient presentations. Anchors all subsequent assessment skills to an evidence-based diagnostic standard.
Chapter 3HideHide detailsSee detailsPharmacological Management Strategies
Pharmacological Management Strategies
Lesson 1 • Anti-inflammatory and Immunomodulatory Agents
Reviews corticosteroids, bisphosphonates, and intravenous immunoglobulin for acute and refractory CRPS. Connects immune pathophysiology to targeted pharmacological intervention.
Lesson 2 • Neuropathic Pain Medications
Covers gabapentinoids, tricyclic antidepressants, and SNRIs with dosing and titration guidance. Directly targets the central sensitisation mechanisms established in Chapter 1.
Lesson 3 • Topical and Local Pharmacotherapy
Examines lidocaine patches, capsaicin, and compounded topical agents for localised symptom control. Offers low-systemic-risk options suitable for polypharmacy patients.
Lesson 4 • Opioid Prescribing and Risk Mitigation
Addresses the limited evidence for opioids in CRPS and frameworks for safe prescribing when indicated. Prepares clinicians to balance pain relief with misuse prevention.
Lesson 5 • Analgesic Ladder Applied to CRPS
Adapts the WHO analgesic framework to CRPS-specific pain mechanisms and response patterns. Establishes a rational starting point for medication selection.
Chapter 4HideHide detailsSee detailsPhysical and Occupational Rehabilitation
Physical and Occupational Rehabilitation
Lesson 1 • Strengthening and Range-of-Motion Programmes
Designs progressive resistance and flexibility protocols adapted to CRPS pain sensitivity. Restores functional capacity while minimising symptom exacerbation.
Lesson 2 • Desensitisation and Graded Exposure
Teaches tactile desensitisation hierarchies and graded exposure to feared movements. Reduces allodynia and fear-avoidance behaviors identified during assessment.
Lesson 3 • Principles of Graded Motor Imagery
Introduces the three-stage GMI protocol: laterality recognition, motor imagery, and mirror therapy. Targets cortical reorganisation identified in Chapter 1 through structured neuroplasticity exercises.
Lesson 4 • Occupational Therapy and ADL Restoration
Covers adaptive equipment, ergonomic modification, and task analysis for daily living activities. Translates rehabilitation gains into real-world functional independence.
Lesson 5 • Aquatic and Complementary Physical Modalities
Evaluates hydrotherapy, TENS, and low-level laser therapy as adjuncts to land-based rehabilitation. Provides evidence-graded options for patients with severe movement intolerance.
Chapter 5HideHide detailsSee detailsPsychological Interventions in CRPS
Psychological Interventions in CRPS
Lesson 1 • Pain Neuroscience Education
Teaches clinicians to deliver structured PNE sessions that reconceptualise pain as a brain output. Reduces threat perception and improves engagement with active rehabilitation.
Lesson 2 • Acceptance and Commitment Therapy
Introduces ACT processes of psychological flexibility, values clarification, and defusion. Provides an alternative framework for patients unresponsive to traditional CBT.
Lesson 3 • Mindfulness-Based Stress Reduction
Covers MBSR protocol delivery, including body scan, breath awareness, and mindful movement. Reduces pain-related distress and improves self-regulation capacity.
Lesson 4 • Cognitive-Behavioural Therapy for Chronic Pain
Applies CBT techniques including cognitive restructuring and behavioural activation to CRPS. Directly addresses catastrophising and fear-avoidance identified as risk factors in Chapter 1.
Lesson 5 • Addressing Comorbid Mood Disorders
Identifies and manages depression and anxiety comorbidities that amplify CRPS disability. Integrates psychiatric referral pathways into the multidisciplinary care model.
Chapter 6HideHide detailsSee detailsInterventional Pain Procedures
Interventional Pain Procedures
Lesson 1 • Sympathetic Nerve Blocks
Covers stellate ganglion and lumbar sympathetic block indications, technique, and evidence. Builds on autonomic pathophysiology from Chapter 1 to justify sympatholytic interventions.
Lesson 2 • Intravenous Regional Anaesthesia
Explains Bier block variants using guanethidine, bretylium, or phentolamine for upper-limb CRPS. Provides a procedural alternative when systemic medications are insufficient.
Lesson 3 • Spinal Cord Stimulation Fundamentals
Introduces SCS mechanism, trial phase, and permanent implantation criteria for refractory CRPS. Prepares clinicians to counsel patients and coordinate with implanting specialists.
Lesson 4 • Intrathecal Drug Delivery Systems
Reviews intrathecal pump indications, drug options, and complication management for severe CRPS. Addresses cases where oral and interventional approaches have failed.
Lesson 5 • Emerging Neuromodulation Techniques
Surveys dorsal root ganglion stimulation, peripheral nerve stimulation, and transcranial approaches. Positions clinicians to evaluate and adopt new technologies as evidence matures.
Chapter 7HideHide detailsSee detailsMultidisciplinary Team Coordination
Multidisciplinary Team Coordination
Lesson 1 • Patient and Family Education
Designs structured education programmes for patients and caregivers covering CRPS mechanisms and self-management. Improves adherence and reduces caregiver burden.
Lesson 2 • Care Coordination Across Settings
Addresses transitions between acute, outpatient, and community care for CRPS patients. Prevents care gaps that lead to symptom relapse and unnecessary hospitalisation.
Lesson 3 • Roles Within the Pain Management Team
Maps the contributions of physicians, psychologists, physiotherapists, and nurses in CRPS care. Establishes shared role clarity as the foundation for effective team function.
Lesson 4 • Outcome Measurement and Quality Improvement
Implements team-level outcome tracking using standardised metrics and audit cycles. Drives continuous improvement in CRPS programme effectiveness.
Lesson 5 • Structured Case Conferencing
Teaches agenda-setting, case presentation formats, and decision-making protocols for MDT meetings. Converts team meetings into efficient, outcome-focused clinical decisions.
Chapter 8HideHide detailsSee detailsAdvanced and Refractory CRPS Management
Advanced and Refractory CRPS Management
Lesson 1 • Chronic Pain and Disability Navigation
Guides clinicians through disability assessment, vocational rehabilitation, and return-to-work planning. Addresses the socioeconomic consequences of long-term CRPS disability.
Lesson 2 • Palliative and Long-Term Supportive Care
Applies palliative care principles to severe, irreversible CRPS with a focus on quality of life. Equips clinicians to shift goals of care when cure is no longer achievable.
Lesson 3 • Defining and Assessing Refractory CRPS
Establishes criteria for labelling CRPS refractory and reassessing prior treatment adequacy. Prevents premature escalation and ensures all standard options are optimised first.
Lesson 4 • Combination and Sequential Therapy Protocols
Designs multimodal regimens that sequence pharmacological, interventional, and rehabilitative treatments. Maximises synergistic effects while managing cumulative adverse event risk.
Lesson 5 • Managing CRPS in Special Populations
Adapts management for paediatric, elderly, pregnant, and cognitively impaired patients with CRPS. Addresses pharmacokinetic, developmental, and ethical considerations unique to each group.
Your valid completion certificate
This course is for you:
Pain medicine physicians: seeking deeper expertise in a notoriously complex condition.
Physical therapists: wanting structured protocols for treating sensitised CRPS patients.
Nurse practitioners: managing chronic pain patients without specialist backup nearby.
Neurologists: encountering CRPS presentations outside their typical diagnostic comfort zone.
Occupational therapists: aiming to restore daily function in movement-avoidant patients.
General practitioners: frustrated by recurring CRPS cases that resist standard treatment.
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